Book Direct Here
and save up to 10%
Compared to Booking.com
Check rooms and rates
From251US$ /night
Check-in
25Dec2025Select date
Check-out
26Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

167 West Main Street, Lexington, Kentucky, United States, 40507
-
Steps from Rupp Arena
Great
8.2
8.7
/10
4.5
4.2
/5

21C Museum Hotel Lexington, a 4-star hotel, features a contemporary art museum and boutique accommodations. It offers a restaurant, bar, and pet-friendly rooms, catering to a modern hospitality experience.

Rooms & Amenities

The hotel features a range of rooms, including City Queen rooms, Deluxe Kings, and spacious two-bedroom suites. Each accommodation includes custom-designed contemporary furnishings, plush beds, Malin + Goetz bath amenities, and original artwork. Guests enjoy free Wi-Fi throughout the property.

Dining & Local Options

Dining options include Lockbox, where the culinary team utilizes local ingredients to create a rotating menu. Nearby cafés like Red River Rockhouse focus on sustainability and also offer locally sourced dishes. Guests can explore various dining experiences in the surrounding area.

Leisure & Events

21C Museum Hotel Lexington includes more than 7000 square feet of exhibition space featuring contemporary art, with regular cultural programming available for guests. The hotel also provides dedicated event spaces, perfect for hosting various events from reunions to corporate meetings.

Location & Transportation

The hotel is strategically located near attractions such as Triangle Park, the University of Kentucky, and Rupp Arena, all within a half-mile radius. Lextran Transit Center is a 6-minute walk for public transportation. Additionally, nearby local breweries and distilleries enhance guests' exploration of Lexington.

Must-do experiences

  • Visit the Lexington Farmers Market on Saturday for fresh local produce.
  • Taste the Hot Brown at the historic Brown Hotel, a local classic.
  • Explore the Mary Todd Lincoln House for a unique historical perspective.
  • Check out the art at the Lexington Art League, showcasing local talent.
  • Walk through the beautiful grounds of the UK Arboretum for tranquility.
View all

Pick the Room That Suits Your Travel Needs

Rooms for singles, families, or groups—many with breakfast, free cancellation, and exclusive airport packages
City Queen Room
2 persons
22 m² 
1 King-size bed
Shower
Coffee machine
Deluxe Queen Room
2 persons
33 m² 
2 King Size Beds
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner King Room
2 persons
40 m² 
1 King-size bed
Shower
Coffee machine
Click button to see more rooms
Show all rooms
Show all roomsLess

View Room Rates & Availability by Date

Check rooms and compare prices for your travel dates today

Facilities

Comfortable Rooms and Convenient Services to Enhance Your Layover

General

  • No smoking on site
  • Free Wi-Fi in public areas
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • 24-hour security
  • Luggage storage
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access
  • Key access

Sports & Fitness

  • Fitness centre
  • Yoga class

Services

  • Paid shuttle service
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Tours/Ticket assistance
  • Welcome drink

Dining

  • In-room breakfast
  • Restaurant
  • Snack bar
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Children's menu

Room features

  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Dressing area
  • Tea and coffee facilities
  • Dining table
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock
Show more

Dining Onsite

At 21C Museum Hotel Lexington, guests can relish diverse dining experiences that highlight American cuisine infused with local flavors. The vibrant setting invites travelers to indulge in wholesome options, catering to various dietary preferences like vegetarian and vegan, making each meal as inclusive as it is delightful.
21C Museum Hotel Lexington Restaurant photo

Lockbox

American, Local
Ambiance
A modern yet cozy atmosphere with artistic touches, perfect for both casual breakfasts and intimate dinners.
Key Offerings
Featuring an array of meal options that cater to vegetarian, vegan, gluten-free, and dairy-free diets. Lockbox serves breakfast and dinner with an emphasis on locally sourced ingredients.
Reservation
Recommended
Breakfast: Wed-Fri 7:00 AM - 11:00 AM; Sat 7:00 AM - 11:00 AM; Sun 10:00 AM - 2:00 PM. Dinner: Wed-Thurs 5:00 PM - 10:00 PM; Fri 5:00 PM - 10:00 PM; Sat 5:00 PM - 11:00 PM; Sun 5:00 PM - 9:00 PM.

Location & Directions

167 West Main Street, Lexington, Kentucky, United States, 40507
Map view
167 West Main Street, Lexington, Kentucky, United States, 40507
Nearby
430 West Vine Street
Rupp Arena
460 m
Museum
Hunt-Morgan House
460 m
Event hall
Lexington Convention Center
440 m
Theatre
Kentucky Theatre
360 m
440 W Short St
Explorium
450 m
University
University of Kentucky
90 m
Park
Triangle Park
340 m
Church
St Paul the Apostle Catholic Church
430 m
Library
Lexington Public Library Ceiling Clock and Foucault Pendulum
260 m
Shopping Area
Victorian Square Shoppes
340 m
Square
Phoenix Park
180 m
Gallery
Limestone Blue
130 m
Lexington Financial Center
Isaac Murphy Memorial Art Garden
140 m
Gallery
Pam Miller Downtown Arts Center
220 m
Gallery
ArtsPlace
240 m
7285 Huron Street
Huron Street Gallery
250 m
Gratz Park
490 m
Restaurants
Bourbon on Rye
70 m
115 W Main St
Corto Lima
180 m
101 West Short Street Corner of West Short and North Limestone Streets
School Sushi
120 m
163 West Short Street
Bluegrass Tavern
150 m
115 Cheapside
Horse And Jockey
190 m
131 Cheapside
Buddha Lounge
190 m
109 N Mill St
Explore Lexington
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Rupp Arena
Rupp Arena
6 minutes' walk
Home to major events and concerts, Rupp Arena also hosts University of Kentucky basketball games, showcasing local sports culture.
Kentucky Theatre
Kentucky Theatre
5 minutes' walk
An iconic theater featuring independent films and live performances, the Kentucky Theatre is a must-visit for movie enthusiasts.
Mary Todd Lincoln House
Mary Todd Lincoln House
9 minutes' walk
The childhood home of Mary Todd Lincoln, this museum offers guided tours showcasing her life and historic insights.
Explorium
Explorium
6 minutes' walk
A hands-on children's museum featuring interactive exhibits, perfect for families looking to engage young minds with fun learning.
Thoroughbred Horse Farm Tours
12 minutes' drive
Guided tours of local horse farms reveal the beauty of Lexington's equestrian culture. Reservations recommended for seasonal availability.
The Arboretum
30 minutes' drive
This beautiful botanical garden features miles of walking trails to relax. Perfect for peaceful strolls or family picnics.
Local Markets
12 minutes' drive
Seasonal farmers' markets offer fresh local produce and crafts. Check schedules for unique cultural experiences and culinary delights.
Bourbon on Rye
Bourbon on Rye
1 minute' walk
A cozy atmosphere featuring local whiskey selections and southern cuisine. Reservations recommended for busy evenings.
Corto Lima
Corto Lima
3 minutes' walk
A vibrant eatery serving Latin-inspired dishes with local ingredients. Known for its fresh ceviche and extensive cocktail menu.
School Sushi
School Sushi
2 minutes' walk
Casual sushi spot offering innovative rolls, sashimi, and an inviting atmosphere. Vegetarian options available.
WoodSongs Old-Time Radio Hour
WoodSongs Old-Time Radio Hour
10 minutes' walk
A unique live music show featuring local talent. Family-friendly, with varied acts making it a delightful evening experience.
Lexington Convention Center
Lexington Convention Center
6 minutes' walk
Hosts various events, including trade shows and concerts. Ideal for guests looking to enjoy local shows during their stay.
How to Navigate the City
City Centre
Lexington5 min  ·  400 m
Airports
Blue Grass Airport (LEX)21 min  ·  13.7 km
Interested in Early Bird Booking Discounts?
Unlock Special Airport Rates Instantly
Check Rates
Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in public areas for free.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
15
Number of rooms:
85
Questions of the users
About 21C Museum Hotel Lexington
Is the hotel pet-friendly? Are there specific charges for bringing pets?
5 November 2024
Yes! There's a one-time pet fee of $50, and there is no limit on the number of pets you can bring along.
What are the parking options available, and are there any fees associated?
18 March 2024
Valet parking is available for $30 per night, which includes unlimited access to your vehicle. Additionally, there is a public parking garage nearby with a maximum daily fee of $12.
Is it possible to arrange an early check-in for my stay?
12 June 2024
Yes, early check-in can be arranged if your room is ready, at no extra charge. To guarantee early access before 4 PM, consider booking the night prior.
Are there any rooms with bathtubs available?
22 January 2024
Rooms featuring separate bathtubs can be found in the Deluxe Suites and the 21c Suite. Additionally, Deluxe Double Queen rooms have tub/shower combos.
Can I park my car rental safely at the hotel?
8 October 2024
Overnight valet parking is offered for $30 a night, with 24/7 access to your vehicle. An alternative public garage is available close to the hotel.
Are there any designated spa services on the property?
15 February 2024
Unfortunately, spa services are not available on-site. However, offsite services and in-room massages can be arranged for your convenience.
Is complimentary Wi-Fi available throughout the hotel?
9 May 2024
Yes, complimentary high-speed Wi-Fi is provided for all guests during their stay.
How safe is the area around the hotel?
27 April 2024
The neighborhood is considered very safe, with 24-hour staff and security presence, plus a police station located just a couple of blocks away.
Are there options for adjoining rooms for larger groups or families?
30 July 2024
Yes, several room types offer connecting options, including Deluxe Suites with Corner Kings and Deluxe Double Queen rooms.
What unique experiences can guests expect during their stay?
1 March 2024
Guests can enjoy rotating contemporary art exhibitions, specialized tours, and unique amenities such as in-room massage services and curated culinary experiences.

Next best alternative

Consider them for your next trip.
Check-in
25Dec2025Select date
Check-out
26Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Need more options?
Check Top hotels near 21C Museum Hotel Lexington
Residence Inn By Marriott Lexington City Center Exterior photo
Mobile-only price

Residence Inn By Marriott Lexington City Center

8.4
Great116 reviews
70m from property
USD 164USD 147
per night
Lexington Marriott City Center Exterior photo
Mobile-only price

Lexington Marriott City Center

8.0
Great100 reviews
111m from property
USD 324USD 291
per night
Hilton Lexington Downtown Hotel Interior photo
Mobile-only price

Hilton Lexington Downtown Hotel

8.1
Great644 reviews
272m from property
USD 92USD 82
per night