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From209US$ /night
Check-in
10Nov2025Select date
Check-out
11Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

700 West Main Street, Louisville, Kentucky, United States, 40202

21C Museum Hotel Louisville, a 5-star boutique hotel, offers a unique combination of contemporary art and luxury accommodations. It features an award-winning restaurant, Proof on Main, and over 9000 square feet of exhibition space.

Rooms & Amenities

Rooms at 21C Museum Hotel Louisville feature modern design elements, including premium Bryte Restorative Sleep Beds. Certain accommodations offer city views, while select rooms include multifunctional furniture designed by local artists.

Dining & Nearby Options

Dining at 21C Museum Hotel is highlighted by Proof on Main, renowned for its southern and Appalachian-inspired cuisine. Guests can enjoy a curated cocktail menu featuring local distillers.

Leisure & Services

Leisure opportunities at 21C include access to curated exhibitions and a nearby ZeroBus for convenient transport to local attractions. The hotel also hosts unique events, such as the Fork & Bottle dinner series featuring regional spirits.

Location & Transportation

21C Museum Hotel features dedicated event spaces accommodating up to 60 guests and is situated within a half mile of notable sites like the Kentucky Museum of Art & Craft and Louisville Slugger Museum. Public bus services are accessible within walking distance.

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Pick the Room That Suits Your Travel Needs

Rooms for singles, families, or groups—many with breakfast, free cancellation, and exclusive airport packages
Room Balcony
2 persons
29 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Room
2 persons
31 m² 
1 King-size bed
Shower
Coffee machine
Corner Suite
2 persons
61 m² 
1 King-size bed
Shower
Coffee machine
Deluxe King Suite
2 persons
46 m² 
1 King-size bed
Shower
Coffee machine
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How to Navigate the City

Explore Every Transit Option Around the Airport

City Centre
Louisville 1.9 km
Airports
Louisville (SDF) 11.9 km

Facilities

Comfortable Rooms and Convenient Services to Enhance Your Layover

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • Safe deposit box
  • 24-hour reception
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Smoke detectors
  • Electric vehicle charging station
  • Fire extinguishers

Sports & Fitness

  • Fitness centre
  • Yoga class

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Outdoor dining area

Business

  • Business centre
  • Meeting/ Banquet facilities
  • Fax/Photocopying

Children

  • Cots

Spa & Leisure

  • Spa & wellness centre
  • Sauna
  • Turkish bath
  • Steam room
  • Full body massage

Room features

  • Air conditioning
  • Heating
  • Mini-bar
  • Soundproofed rooms
  • Patio
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV

Room decor

  • Carpeted floor
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Location & Directions

700 West Main Street, Louisville, Kentucky, United States, 40202
Map view
700 West Main Street, Louisville, Kentucky, United States, 40202
Nearby
Museum
Louisville Slugger Museum & Bat Factory
180 m
Museum
Muhammad Ali Center
280 m
Museum
Kentucky Science Center
140 m
Museum
The Frazier History Museum
260 m
Museum
Kentucky Museum of Art and Craft
70 m
528 W Main St
Evan Williams Bourbon Experience
200 m
Gallery
Flame Run Glass Studio and Gallery
300 m
500 W Main St
The Belvedere
250 m
Night club
Jimmy Can't Dance
90 m
801 W Main St
Michter's Fort Nelson Distillery
150 m
Library
Sons of the American Revolution Genealogical Research Library
190 m
120 N 10th St
Kentucky Peerless Distilling Co
480 m
401 W River Rd
Belle of Louisville Riverboats
580 m
Restaurants
Proof On Main
10 m
702 West Main Street
Mussel & Burger Bar Downtown
60 m
113 S 7th St Located in Louisville's Central Business District
Bristol Bar & Grille
110 m
614 W Main St
Atlantic No. 5
160 m
605 W Main St Located in Louisville's Central Business District.
Los Aztecas Mexican Restaurant
180 m
445 E Market St
Vincenzo's Italian Restaurant
430 m
150 S 5th St
Jockey Silks Bourbon Bar
480 m
140 N 4th St 2nd Floor - West Tower
Dish on Market
470 m
434 W Market St
Quiznos
540 m
223 S 5th St
Swizzle Dinner & Drinks
530 m
140 N Fourth St 25th Floor
Cafe Magnolia
590 m
140 N 4th St Galt House Hotel
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Check-in
10Nov2025Select date
Check-out
11Nov2025Select date
Rooms and Guests2 Guests, 1 Room