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From166US$ /night
Check-in
16Nov2025Select date
Check-out
17Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105

Home2 Suites By Hilton Sioux Falls Sanford Medical Center is a 3-star all-suite hotel featuring kitchens and pet-friendly accommodations. Guests have access to amenities like free breakfast and an indoor pool, all connected to Sanford Medical Center via a climate-controlled skywalk.

Rooms & Amenities

The rooms at Home2 Suites By Hilton offer a kitchen with full-size refrigerators, microwaves, and a flat-screen TV. Suites include free WiFi and a comfortable seating area, making for a home-like environment. Pet-friendly options are available with additional fees.

Dining & Nearby Options

Guests can start their day with a complimentary breakfast buffet featuring various options. Nearby dining includes Azteca and Domino's Pizza, located just 0.5 miles from the hotel.

Leisure & Fitness

Recreational facilities include an indoor saline swimming pool and hot tub, along with a 24-hour fitness center. Guests can also utilize the unique Spin2Cycle facility, combining laundry and fitness options.

Business & Location

Home2 Suites by Hilton Sioux Falls offers business travelers a dedicated business center and meeting space totaling 950 square feet. The hotel is conveniently located near the Denny Sanford Premier Center and downtown Sioux Falls, enhancing accessibility.

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Pick the Room That Suits Your Travel Needs

Rooms for singles, families, or groups—many with breakfast, free cancellation, and exclusive airport packages
King Studio Suite Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
King Studio Suite Hearing Access or Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
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How to Navigate the City

Explore Every Transit Option Around the Airport

City Centre
Sioux Falls800 m
Airports
Sioux Falls Regional (FSD) 7.9 km
Stronsay (soy) 86.3 km

Facilities

Comfortable Rooms and Convenient Services to Enhance Your Layover

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Location & Directions

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
290 m
1001 SW Avenue
Sioux Falls Stadium
530 m
Restaurants
The Co-op of Sioux Falls
860 m
410 W 18th St
Azteca
1.1 km
811 S Minnesota Ave
Toppers Pizza
1.1 km
817 S Minnesota Ave
Taco John's
1.0 km
1100 S Minnesota Ave
Papa John's Pizza
1.1 km
711 S Minnesota Ave
Abelardo's Mexican Food
1.1 km
1200 S Minnesota Ave
Pho Quynh
960 m
1100 W 12th St
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Check-in
16Nov2025Select date
Check-out
17Nov2025Select date
Rooms and Guests2 Guests, 1 Room