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From166US$ /night
Check-in
15Feb2026Select date
Check-out
16Feb2026Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
-
Close to Falls Park
Great
8.6
9.3
/10
4.5
/5

Home2 Suites By Hilton Sioux Falls Sanford Medical Center is a 3-star all-suite hotel featuring kitchens and pet-friendly accommodations. Guests have access to amenities like free breakfast and an indoor pool, all connected to Sanford Medical Center via a climate-controlled skywalk.

Rooms & Amenities

The rooms at Home2 Suites By Hilton offer a kitchen with full-size refrigerators, microwaves, and a flat-screen TV. Suites include free WiFi and a comfortable seating area, making for a home-like environment. Pet-friendly options are available with additional fees.

Dining & Nearby Options

Guests can start their day with a complimentary breakfast buffet featuring various options. Nearby dining includes Azteca and Domino's Pizza, located just 0.5 miles from the hotel.

Leisure & Fitness

Recreational facilities include an indoor saline swimming pool and hot tub, along with a 24-hour fitness center. Guests can also utilize the unique Spin2Cycle facility, combining laundry and fitness options.

Business & Location

Home2 Suites by Hilton Sioux Falls offers business travelers a dedicated business center and meeting space totaling 950 square feet. The hotel is conveniently located near the Denny Sanford Premier Center and downtown Sioux Falls, enhancing accessibility.

Must-do experiences

  • Stroll through Falls Park for stunning waterfalls and trails.
  • Savor the Jodi's Deli sandwich at the nearby Falls Overlook Cafe.
  • Visit the Sioux Falls Historic Downtown for local shops and murals.
  • Explore the Sioux Empire Fair if you're here in August for fun.
  • Don't miss the Canton Depot Museum for local history and charm.
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Pick the Room That Suits Your Travel Needs

Rooms for singles, families, or groups—many with breakfast, free cancellation, and exclusive airport packages
King Studio Suite Non-Smoking
2 persons
435 sq. feet 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Non-Smoking
2 persons
435 sq. feet 
2 King Size Beds
Heating
Air conditioning
King Studio Suite Hearing Access or Non-Smoking
2 persons
435 sq. feet 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
2 persons
435 sq. feet 
2 King Size Beds
Heating
Air conditioning
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Facilities

Comfortable Rooms and Convenient Services to Enhance Your Layover

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Location & Directions

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
1000 ft
1001 SW Avenue
Sioux Falls Stadium
1800 ft
Restaurants
The Co-op of Sioux Falls
2900 ft
410 W 18th St
Azteca
3600 ft
811 S Minnesota Ave
Toppers Pizza
3600 ft
817 S Minnesota Ave
Taco John's
3500 ft
1100 S Minnesota Ave
Papa John's Pizza
3700 ft
711 S Minnesota Ave
Abelardo's Mexican Food
3500 ft
1200 S Minnesota Ave
Pho Quynh
3200 ft
1100 W 12th St
Explore Sioux Falls
Local Highlights
Top Attractions
Activities
Dining
Entertainment
Sioux Empire Medical Museum
4 minutes' walk
Medical artifacts and history showcase Sioux Falls' health advancements. Engaging for all ages.
Great Plains Zoo & Delbridge Museum of Natural History
6 minutes' drive
Home to diverse animal species and educational exhibits in a lovely setting. Great for families.
Michelangelo's David replica
15 minutes' walk
A life-sized replica of Michelangelo's masterpiece located in a beautiful park, perfect for a quick visit.
The Pettigrew Home and Museum
4 minutes' drive
Historic home displaying local history and culture. Notable for its preserved architecture.
Sertoma Butterfly House & Marine Cove
9 minutes' drive
A tropical environment filled with butterflies and marine exhibits. Family-friendly and serene.
Sioux Falls Bike Trail
25 minutes' walk
Scenic trail suitable for biking and walking. Ideal for outdoor enthusiasts looking for an adventure.
Midco Aquatic Center
16 minutes' walk
Indoor water park featuring slides and pools. Perfect for families or anyone seeking some fun.
The Co-op of Sioux Falls
11 minutes' walk
Casual dining with a focus on local ingredients. Excellent farm-to-table dishes in a welcoming environment.
Azteca
13 minutes' walk
Vibrant Mexican restaurant known for authentic flavors and colorful decor. Great options for families.
Toppers Pizza
13 minutes' walk
Casual pizza joint with unique toppings and quick service. Perfect for a relaxed meal or takeout.
Lucky Lady Casino
15 minutes' walk
A lively casino offering gaming and dining options. Great entertainment spot for adults.
Sioux Falls Stadium
7 minutes' walk
Home to local sports events. Exciting atmosphere for fans and families to enjoy live games.
Eastbank Art Gallery
25 minutes' walk
Local art gallery showcasing works from regional artists. A culturally enriching experience for all.
How to Navigate the City
City Centre
Sioux Falls10 min  ·  2700 ft
Airports
Sioux Falls Regional Airport (FSD)12 min  ·  4.9 mi
Stronsay Airport (soy)130 min  ·  53.6 mi
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Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
is available in for free.
Breakfast
A buffet breakfast is served at affordable prices. 
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
4
Number of rooms:
76
Questions of the users
About Home2 Suites By Hilton Sioux Falls Sanford Medical Center
Are the pool and hot tub currently available for guests to use?
20 November 2024
Yes, both the pool and hot tub are open for use by guests.
Do you provide cribs or playpens for infants during our stay?
15 January 2025
Pack and plays are available upon request.
Is it allowed to bring pets, and what is the associated fee?
5 February 2025
Pets are welcome with a flat fee of $75 plus tax for the entire stay.
Are there any discounts available for families of patients at Sanford Hospital seeking extended stays?
10 March 2025
Discounts are available for Sanford patients and their families. Please contact the hotel directly for specific rates on extended stays.
How far is the hotel from the nearest airport?
25 April 2025
The hotel is approximately a 10-minute drive from the airport.
Is there a limit on the size or number of pets allowed per room?
30 May 2025
Up to two pets are allowed per room, regardless of size.
Can guests request a recliner for comfort in their room?
15 June 2025
Recliners are available, but availability cannot be guaranteed.
What is the minimum age requirement to check in?
1 July 2025
Guests must be at least 18 years old to check in.
Are there any restaurants in the vicinity of the hotel?
20 August 2024
Several dining options are located just minutes away from the hotel.
Is there an option to pay cash instead of using a card if it was used for online booking?
5 September 2024
Yes, cash payment is allowed at check-in, provided the booked nights and a $100 cash deposit are covered.
What time can I check out if I need a little extra rest?
15 October 2024
A late checkout can be arranged until 1 PM at no additional cost; extended checkout between 1 PM and 3 PM will incur a half-day fee.
What differentiates a queen room from a suite at this hotel?
25 November 2024
All accommodations are suites equipped with full kitchens, while room configurations include either king studios or queen studios.

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