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From166US$ /night
Check-in
25Jun2025Select date
Check-out
26Jun2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105

Home2 Suites By Hilton Sioux Falls Sanford Medical Center is a 3-star all-suite hotel featuring kitchens and pet-friendly accommodations. Guests have access to amenities like free breakfast and an indoor pool, all connected to Sanford Medical Center via a climate-controlled skywalk.

Rooms & Amenities

The rooms at Home2 Suites By Hilton offer a kitchen with full-size refrigerators, microwaves, and a flat-screen TV. Suites include free WiFi and a comfortable seating area, making for a home-like environment. Pet-friendly options are available with additional fees.

Dining & Nearby Options

Guests can start their day with a complimentary breakfast buffet featuring various options. Nearby dining includes Azteca and Domino's Pizza, located just 0.5 miles from the hotel.

Leisure & Fitness

Recreational facilities include an indoor saline swimming pool and hot tub, along with a 24-hour fitness center. Guests can also utilize the unique Spin2Cycle facility, combining laundry and fitness options.

Business & Location

Home2 Suites by Hilton Sioux Falls offers business travelers a dedicated business center and meeting space totaling 950 square feet. The hotel is conveniently located near the Denny Sanford Premier Center and downtown Sioux Falls, enhancing accessibility.

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Pick the Room That Suits Your Travel Needs

Rooms for singles, families, or groups—many with breakfast, free cancellation, and exclusive airport packages
King Studio Suite Non-Smoking
Max:
4 persons
435 sq. feet 
Bed options:
1 King-size bed
Heating
Air conditioning
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Queen Studio Two Queen Beds Non-Smoking
Max:
6 persons
435 sq. feet 
Bed options:
2 King Size Beds
Heating
Air conditioning
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King Studio Suite Hearing Access or Non-Smoking
Max:
4 persons
435 sq. feet 
Bed options:
1 King-size bed
Heating
Air conditioning
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How to Navigate the City

Explore Every Transit Option Around the Airport

City Centre
Sioux Falls2700 ft
Airports
Sioux Falls Regional (FSD) 4.9 mi
Stronsay (soy) 53.6 mi

Facilities

Comfortable Rooms and Convenient Services to Enhance Your Layover

General

  • No smoking on site
  • Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Location & Directions

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
1000 ft
1001 SW Avenue
Sioux Falls Stadium
1800 ft
Restaurants
Azteca
3600 ft
811 S Minnesota Ave
The Pita Pit
2900 ft
925 South Minnesota Avenue
Toppers Pizza
3600 ft
817 S Minnesota Ave
Taco John's
3500 ft
1100 S Minnesota Ave
Giliberto's Mexican Taco Shop
4000 ft
712 South Minnesota Avenue
Papa John's Pizza
3700 ft
711 S Minnesota Ave
Taco Bell
3600 ft
812 S Minnesota Ave
Slim Chickens
4200 ft
1517 S Minnesota Ave
Pho Quynh
3200 ft
1100 W 12th St
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Check-in
25Jun2025Select date
Check-out
26Jun2025Select date
Rooms and Guests2 Guests, 1 Room